[3] Thermophiles are found in various geothermally heated regions of the Earth, such as hot springs like those in Yellowstone National Park (see image) and deep sea hydrothermal vents, as well as decaying plant matter, such as peat bogs and compost.
Some are lithotrophs that oxidize sulphur to create sulfuric acid as an energy source, thus requiring the microorganism to be adapted to very low pH (i.e., it is an acidophile as well as thermophile).
For example, the GC-content levels in the coding regions of some signature genes were consistently identified as correlated with the temperature range condition when the association analysis was applied to mesophilic and thermophilic organisms regardless of their phylogeny, oxygen requirement, salinity, or habitat conditions.
[9] Thermophilic fungi have great biotechnological potential due to their ability to produce industrial-relevant thermostable enzymes, in particular for the degradation of plant biomass.
When these organisms are exposed to the DNA damaging agents UV irradiation, bleomycin or mitomycin C, species-specific cellular aggregation is induced.
[11][12] In S. acidocaldarius, UV-induced cellular aggregation mediates chromosomal marker exchange with high frequency.