The Thessaloniki Inner Ring Road (Greek: Εσωτερική Περιφερειακή οδός Θεσσαλονίκης) is a dual carriageway ring road encircling most of the Thessaloniki Urban Area in Central Macedonia, Greece.

Planned in 1975 and put into service in the 1990s, it consists of the Western Ring section (Δυτική Περιφερειακή), and of the main Inner Ring section (Greek: Εσωτερική Περιφερειακή).

With three lanes per direction it carries over 120.000 cars per day, making it one of the country's most busy highway sections.

Passing by the municipalities Ampelokipoi-Menemeni, Kordelio-Evosmos and Pavlos Melas it joins the A24 motorway (Promachonas–Nea Moudania) near Efkarpia.

The Western Ring section has been recently upgraded to full Motorway standard in its biggest part with five new intersections have been built.