After winning honours including four La Liga titles, the UEFA Champions League and the FIFA Club World Cup for Barcelona, he was signed by Bayern Munich for €25 million in 2013.

In Germany, Thiago won 16 trophies, including the Bundesliga seven times in a row, and the UEFA Champions League as part of a continental treble in his final year at the club.

Thiago was part of the provisional squad for Spain in the 2014 FIFA World Cup but withdrew due to a knee injury.

Thiago was born in San Pietro Vernotico, Italy, when his father Mazinho (player for the Brazil national team from 1989 to 1994) was playing for nearby U.S. Lecce.

[9] On 17 May 2009, aged 18, Thiago made his debut for the first team when he came on as a substitute for Eiður Guðjohnsen in the 74th minute at RCD Mallorca for his only appearance of the season.

[11] On 20 February 2010, after coming on as a substitute for Yaya Touré in the 76th minute, Thiago scored his first goal for Barcelona in a 4–0 home win against Racing de Santander.

[13] He ended the 2010–11 season with 17 games, three goals, and three assists, and was an unused substitute as Barcelona won the 2011 UEFA Champions League final against Manchester United at Wembley Stadium.

[34] Four days later, he again replaced Lahm in a DFB-Pokal quarter-final at Bayer Leverkusen, scoring the winning goal in the penalty shootout after a goalless draw.

[36] Six days later, he headed in Juan Bernat's cross for the opening goal of a 6–1 rout to overturn the first leg deficit against Porto, helping Bayern advance to the Champions League semi-finals.

[42] On 17 March, Thiago scored a goal in a brilliant comeback against Juventus as his side came from 2–0 down to gain a 4–2 victory in the Champions League round of sixteen tie.

[49] On 16 February 2017, he scored two goals and provided one assist as Bayern defeated Arsenal with a 5–1 victory in the first leg of the Champions League round of sixteen tie.

[52] Because of an injury, Thiago could not play his club's first competitive match of the season, in the 2017 DFL-Supercup where Bayern won against Borussia Dortmund 5–4 on penalties on 6 August 2017.

[53][54] On 26 October, he scored an equalizing goal against RB Leipzig to make it 1–1 and later Bayern went on to win the DFB-Pokal second-round match 5–4 on penalties.

Anderlecht in the Champions League group stage match and was confirmed by his club manager Jupp Heynckes that he will be out for a long period of time.

[58][59] On 4 April, he scored a header which secured Bayern Munich a 2–1 away victory over Sevilla FC in the first leg of their Champions League quarter-final tie.

On 12 August 2018, Thiago played the first competitive match of the season under the new club manager Niko Kovač and also scored a goal in a 5–0 victory over Eintracht Frankfurt as Bayern won the 2018 DFL-Supercup.

[64] Amidst heavy media speculation linking him with a potential move to Liverpool,[65] Thiago played for Bayern in the Champions League quarter-final against his former team Barcelona, participating in an 8–2 demolition of the Catalan outfit.

[70][71] Thiago made his debut for Liverpool on 20 September, coming off the bench at half-time as the visitors won 2–0 against Chelsea at Stamford Bridge.

He suffered a knee injury towards the end of the game as Richarlison made a tackle that would give him a straight red card after the challenge.

[77] On 24 November 2021, Thiago cut across the ball to score with a 25-yard strike (his first goal of the 2021–22 season) in a 2–0 home win for Liverpool against FC Porto in the UEFA Champions League group stage.

[78] On 27 February 2022, Thiago was due to start the 2022 EFL Cup final, but sustained an injury in the warm-up and was replaced by Naby Keïta.

[79] On 19 April, Thiago earned a standing ovation from the spectators for his performance when he was replaced by Naby Keita in a 4–0 victory against Manchester United.

[80] On 14 May 2022, Thiago started for Liverpool in the 2022 FA Cup final, defeating Chelsea in a 6–5 victory on penalties after the game ended 0–0 in extra time.

On 18 June 2013, he scored a hat-trick in the 2013 UEFA European Under-21 Championship final as Spain defeated Italy 4–2 to win their fourth title.

Bayern Chief Executive Karl-Heinz Rummenigge said, "A young man who wanted to come back at the World Cup, and suddenly his dreams are burst.

"[99] On 2 October 2015, with the team's place in the tournament already assured, Thiago was re-called by manager Vicente del Bosque for the first time since his injury,[100] and ten days later featured in their 1–0 UEFA Euro 2016 qualifying win away to Ukraine.

Álvaro Odriozola sent in a cross from the right side of the box and Thiago directed the ball into the bottom corner from close range with his head.