In September 1958, This Week filmed George Harrison Marks and Pamela Green at their photography studio in Gerrard Street.

However, the night it was to be broadcast Pope Pius XII died and the programme was cut, and the interview never shown.

was an exposé on the National Front in 1974, which led to the party's members firing their Chairman John Tyndall and National Activities Organiser Martin Webster two weeks later as a result of the revelations on the show from former NF Chairman John O'Brien of their neo-Nazi paramilitary pasts and continued links.

In 1976 the episode Death in the West believed to contain the first recorded admission from a tobacco company representative that smoking causes health problems resulted in an injunction from Philip Morris International.

During its run, the programme's presenters included Ludovic Kennedy, James Cameron, Jonathan Dimbleby, Robert Kee, Dan Farson, Jeremy Thorpe (who became leader of the Liberal Party), Desmond Wilcox, Bryan Magee, Peter Taylor (noted for his coverage of Northern Ireland), Denis Tuohy, John Morgan and Yvonne Roberts.