The Thomas C. Wilkinson House is a historic building located in the West End of Davenport, Iowa, United States.

[2] The Thomas C. Wilkinson House is an Italian Villa style home that sits on a large lot high above street level.

The two-story house is frame construction with a front gable, L-plan main block.

The windows on the west wing appear to be from the turn of the 20th-century and suggest this portion of the house was built later than the rest of the structure.

[2] The house features a bracketed cornice on the main block, an entrance porch with a spindle frieze and wrought iron railings.