Thomas Charles O'Reilly (February 22, 1873 – March 25, 1938) was an American prelate of the Catholic Church who served as bishop of the Latin Diocese of Scranton in Pennsylvania from 1928 to 1938.

[2] O'Reilly was ordained to the priesthood for the Diocese of Cleveland by Cardinal Francesco di Paola Cassetta on June 4, 1898.

He was chancellor (1909–1916) and vicar general (1916–1921) of the diocese before serving as pastor of the Cathedral of St. John the Evangelist.

[2] On December 16, 1927, O'Reilly was appointed the third Bishop of Scranton, Pennsylvania, by Pope Pius XI.

[3] During his tenure, he established seven parishes and fourteen schools in the diocese, despite the economic ravages of the Great Depression.