They had five[5] or eight[6][unreliable source] children, including John, who succeeded as 2nd Baron Darcy of Chiche.

His position in court was assisted though his relations with the de Veres and his cousin, Edward Seymour, 1st Duke of Somerset.

He was sworn of the Privy Council on 24 January 1550, and on 2 February he was appointed Vice-Chamberlain of the Household and Captain of the Yeomen of the Guard.

On 5 April 1551, he was created Baron Darcy of Chiche to serve as Lord Chamberlain of the Household, and in this role, he led a commission to reform the revenue courts.

He was one of the signatories to the letters patent enabling Lady Jane Grey to succeed Edward VI, and this support led to his house arrest by Mary I.