Born in Marylebone, London, eldest son of the 1st Earl and his wife Harriet Hale, he was educated at Harrow and Trinity College, Cambridge.
[1] In 1818 he was elected Whig Member of Parliament for his father and grandfather's old seat of Richmond, becoming representative for York twelve years later.
Zetland was a senior member of the Jockey Club and won The Derby and St Leger Stakes with his horse Voltigeur in 1850.
[2] In the year of his succession to the earldom, he was appointed Lord Lieutenant and Custos Rotulorum of the North Riding of Yorkshire, and in 1861 became a Knight of the Thistle.
He resigned the Order on being made a Knight Companion of the Garter in 1872, and died the following year at Aske Hall, Yorkshire.