Thomas Henry Macpherson (June 1, 1842 – June 17, 1903) was a Scottish-born merchant and political figure in Ontario, Canada.
He represented Hamilton in the House of Commons of Canada from 1896 to 1900 as a Liberal.
Macpherson was employed at a banking house in England and came to Ontario in 1871.
He became the senior member of a wholesale grocery in Hamilton.
Macpherson served as president of the Hamilton Board of Trade.