Thomas Hopkinson (April 6, 1709 – November 5, 1751) was a lawyer, public official, and prominent figure in colonial Philadelphia, Pennsylvania.

As a young barrister, he was appointed deputy to Charles Read, Clerk of the Orphans' Court of Philadelphia.

[1] Hopkinson held a number of legal and judicial positions, including Justice (1749), and Judge of the Vice Admiralty of the Province (1744-5).

As a merchant, Hopkinson acted as agent for several London firms, and in partnership with William Coleman, imported and sold a wide variety of goods, including fabrics, spices, gunpowder and iron.

In 1747 he was the first to detect the incursions of the Spanish into Delaware Bay and was a leader in alerting public opinion as well as raising funds for the defense of the city.