Most recently, during the 2017 season, the Bulldogs went 12-1 and notched the program's 700th win when they defeated cross-town rival Thomas County Central High School.

The Bulldogs made the Semifinals in 2019 after starting 0-3 and finishing 6-4 and winning another region championship, losing to the eventual state champions.

While there was a suspension of the two series in the late 1990s, the rivalries has recently been picked back up and occurs in early part of the season each year.

The school has produced major college and NFL players including William Andrews, Mike Bobo, Shawn Jones, Mike Jones (University of Georgia), Charles Bostick (Georgia Southern University), Eric Curry, Guy McIntyre, Sheddrick Wilson (Louisiana State and Houston Oilers) and Brandon Thompson of the Cincinnati Bengals.

In the 2016 season, the Thomasville High School tennis team wore their wildly popular "Black Out" uniforms.

In 2017, the boys team debuted a similar "Black Out" uniform, this year consisting of a collared shirt and embroidered diamond T logo.

During the 1974 season, the Thomasville Doubles team of Virginia Balfour and Greer Becknell attained the title of AAA State Runner-Up.

Two singles players for the boys' team reached the state final four, when the tournament consisted of individual play.

These teams were Ann Rumble and Penny Dollar (1968), Carla Thornton and Joy Alligood (1971 AAA), Virginia Balfour and Greer Becknell (1973), Dayna Leak and Donna Leak (1976 AAA), Blake Brookered and Mike Clay (1973), and Jesse Booth and Bobby Balfour (1972), and Charles Weir and John Everett (1980 AAA).