It was founded in 1998 in memory of Supachai Yamchuti, the founder of Mubankru Technological College.
Mubankru Technological College was established in 1969 for offering a Diploma in Vocational Education (Por-Wor-Sor) program and is located on the same street as Thonburi University.
The organisation structure body and the administration system of Thonburi University and Mubankru School were coordinated within a short period of time.
Gradually a branch of Mubankru was established in Lamphun Province in the northern part of Thailand.
With this aim in mind, Thonburi University was set up, with the main objective of imparting higher educational degree programs.