Dr. Geert Smeekens replaces Michael Bastiaens in the doctor's office alongside Ann De Decker.
Eva begins a relationship with Maarten who turns out to be just as jealous and obsessed as Jan, his brother and her late husband.
Later on this season, civil law notary Peter Vlerick, played by Geert Hunaerts, will be introduced as a Bastiaens family friend.
Femke rejects him, and Raffael sets hotel Ter Smissen on fire during Rosa and Waldek's wedding party.
Paulien becomes pregnant and Bram changes his mind a few times but concludes that he doesn't want to be a father and that Pauline should have an abortion.
Doctor Ann informs the police, while Peter makes Femke leave and Raffael is put under psychiatric care.
Rosa and Jenny start a bed and breakfast, overcoming the establishment's prior image as a swingers club.
Leo moves his taxi company; he falls in love with Jenny and when he tries to inform his girlfriend, Yvette, she suffers a stroke.
In court Tom convinces the judge that Fien died due to a hereditary heart disease, and Guy is released.
They promise not to have secrets, but Tibo is hiding a fifteen-year-old daughter, Jana, who lives with her lesbian mother, Ellen.
Mayra moves in with Ann and starts a jewelry business, but her inventory is stolen by Kasper, the son of Rosa and Waldek, who owes money to criminals.
Eddy returns and, after successfully hobby-brewing beer with Frank and Waldek, they buy a brewery with Geert and David as investors.
Later, Guy holds Sandrine, Mayra and Marianne hostage, which Peggy uses as an argument that the doctor's home is no safer.
After Geert learns his wife Marianne slept with David he wants divorce and leaves the practice, replaced by Judith.
Mayra also wants to have a child, and she and Ann convince Kurt to be a sperm donor but he changes his mind when this becomes public knowledge.
Paulien asks Adil and Lowie to pose half naked for a book's cover photo, and they agree as long as their faces aren't shown.
Franky returns but won't attend and has shocking news: he's divorced Tibo – and will be undergoing gender reassignment surgery.
Marianne reads emails on Hélène's phone and suspects she is having a secret affair with a man named Henri and is about to lose €160,000.
Moments later, Ann and Mayra rush in to the sound of screams and find Marianne holding a bloody knife over a dead Geert.
Charité starts a relationship with Renzo but is astonished when her husband - thought killed in a civil war - appears.
Sam's business is almost bankrupt and decides to do a job off the books, but the client refuses to pay since they didn't have a contract.
Julia goes crazy, pouring boiling water over Luc and putting sleeping pills in his cookies, risking his life.
After a medical test, it turns out Adil his semen is of low quality so he and Paulien start an In vitro fertilization-treatment.
After babysitting for Emile, a pupil in Olivia's class whose father Lander works at the taxi company, Bob realizes he does like children.
Jasper, the boxing teacher of Ann, is found guilty of the murder on the manageress of pub "Bar Madam", the rape on Tilly and sales of drugs.
Jacques starts a part-time job as real estate salesman in the company of Reinhilde and goes to Spain for some time to sell some houses.
Harry Peeters also stops his project, but as he convinced Louis to make some changes in the standard contract, he does not have to pay BOWIE at all.
A charming man brings a visit to pub "Bar Madam" but steals money from the till so Angèle is temporary fired as she was responsible.
She admits or feigns to also have feelings for Ilias but he must prove himself by doing all kind of wager tasks such as going to class in a woman's outfit.
The new song was created by Will Tura and Steve Willaert with lyrics by Frank Dingenen, an actor who had played a guest role which he reprised at the start of season 13.