Thuso Mpuang (born 15 August 1985) is a South African sprinter who specializes in the 200 metres.

[1] Mpuang represented South Africa at the 2008 Summer Olympics in Beijing.

He competed at the 4x100 metres relay together with Leigh Julius, Ishmael Kumbane and Hannes Dreyer.

In their qualification heat they did not finish due to a mistake in the baton exchange and they were eliminated.

[1] He also took part in the 200 metres individual, running the distance in 20.87 seconds and only placing sixth in his heat.