"[6] Californian writer De Moss Bowers remarked in 1909 that Tiburón was "almost inaccessible" and that it had an "interior of which no white man has ever explored".

Although never confirmed by the sole survivor, it was suspected the Seri people were responsible for the disappearances, as it was not the first time an incident of this nature had occurred.

[9][10] During the 1960s and early 1970s, a small hunting and fishing camp on the northern end of the island was operated by Jesus Olivas, a resident of Hermosillo.

The Mexican government, through a decree by President Echeverría, gave the Seri "recognition and title of communal property" (reconocimiento y titulación de terrenos comunales) with respect to Tiburón Island in 1975.

Bighorn sheep were introduced to the island in the 1980s;[11] hunting is managed by the tribal government in coordination with Mexican federal authorities.

It is also home to a unique subspecies of coyote (Canis latrans jamesi)[12] and mule deer (Odocoileus hemionus sheldoni)[13] that are endemic to the island.