Ticvaniu Mare (Hungarian: Nagytikvány; Vlax Romani: Tikvaja Bare) is a commune in Caraș-Severin County, western Romania with a population of 1951 people.

It is composed of four villages: Cârnecea (Kernyécsa), Secășeni (Krassószékás), Ticvaniu Mare and Ticvaniu Mic (Kistikvány).