2OSG, 3E17941421873ENSG00000119139ENSMUSG00000024812Q9UDY2Q9Z0U1NM_201629NM_001369870NM_001369871NM_001369872NM_001369873NM_001369874NM_001369875NM_001198985NM_011597NM_001360391NM_001360392NM_001376368NP_001163885NP_001163886NP_001163887NP_004808NP_963923NP_001185914NP_035727NP_001347320NP_001347321Tight junction protein ZO-2 is a protein that in humans is encoded by the TJP2 gene.

[5] Tight junction proteins (TJPs) belong to a family of membrane-associated guanylate kinase (MAGUK) homologs that are involved in the organization of epithelial and endothelial intercellular junctions.

TJPs bind to the cytoplasmic C termini of junctional transmembrane proteins and link them to the actin cytoskeleton [supplied by OMIM].

[6] Tight junction protein 2 has been shown to interact with tight junction protein 1,[7][8][9] band 4.1,[10] occludin[7][8][11] and USP53.

[12]