She was the editor of digital scholarly editions at Romantic Circles from 2005 to 2019 and has been featured as a pre-eminent teacher of creative/narrative nonfiction with the Teaching Company / Great Courses.
It was described by Charles McGrath of the New York Times as "smart and insightful and points out that eighteenth-century writers took a certain amount of borrowing for granted.
"[5] Cited in a 2020 Guardian article on the Led Zeppelin copyright case verdict, Mazzeo's book was called a "seminal study of plagiarism in the Romantic period."
Mazzeo continues to work in and lecture on intellectual property law in the international context, especially as related to appellation, geographic brand, and the wine industry.
In 2009, Mazzeo informally studied perfume making with Ron Winnegrad at International Flavors and Fragrances in New York City.
Sisters in Resistance recounts the history of three women who helped to save evidence of German war crimes and passed them to the Allies for use at Nuremberg.
[16] Kirkus Reviews wrote that "Mazzeo's probing book delves intriguingly into the 'moral thicket' into which a group of strangers found themselves plunged during the long, dark days of World War II".
[17] The Times Literary Supplement called the book a "thrilling historical drama tightly focused on the fate of the diaries after Ciano's fall from grace."
In 2023, St. Martin's Press acquired Mazzeo's current work-in-progress, a biography of the nineteenth-century mariner Mary Ann Patten, the first woman to command a merchant vessel in the United States.
Patten took over from her stricken sea-captain husband as the clipper ship, Neptune's Car, was transiting Cape Horn, captained the vessel through a weeks' long storm and icebergs off the coast of Antarctica in the 1850s.