The school was originally named the New Hampshire Conference Seminary of the Methodist Episcopal Church and was located in the town of Northfield.

Most students were from neighboring towns, but some traveled from as far as Vermont and Boston to attend the new Methodist school.

During this period, the school underwent major changes, including the addition of a new gymnasium, library, chapel, dormitory, and the purchase of 49 acres (20 ha) of land adjacent to campus.

In 2013, Chris Burch, Class of 1972, announced at an all-school meeting that he would be donating $1.3 million for the construction of an artificial turf field on the Hill.

She is known for leading the school through COVID-19,[6] the Charles E. Tilton Mansion restoration, and the Knowles Hall renovation.

At Tilton classes are held Monday through Friday; the afternoons are reserved for athletics and club activities.

The school also inducts a small group of highly ambitious students into the National Honor Society every year.

The girls' varsity basketball team has also won the Lakes Region League Championship every year since 2010.

Students may participate in intramural sports, including club hockey, basketball, squash, dodgeball, skiing, rock climbing, hiking, and dance.

Each year, a group of students travel to the Dominican Republic on their spring break in March to work with the Batey Foundation and help build community centers in impoverished areas.

Skinner Tower, constructed in 2007 and designed by Scott Simons Architects, is located just west of Plimpton Hall and connects to that building.

The atrium of the tower is used as a common space for students during free periods, as an art gallery, and sometimes as a dance floor for school socials.

Maloney Hall, also constructed in 2007, occupies 15,000 square feet (1,400 m2) and houses 20 senior girls, as well as three faculty apartments.

The Fred Andrew Smart Chapel was transported in 1965 to Tilton's campus from its original home in Canterbury, New Hampshire.

Construction began when alumnus J. Christopher Burch ('72) made the largest single donation in the school's history in the spring of 2013.

The Memorial Gymnasium was built shortly after World War II to honor Tilton students who had served and died for their country.

In 1998, the building was completely renovated and rededicated as the Memorial Athletic and Recreational Center (MARC).

In the building is a memorial honoring Tilton students who have died in battle, dating back to the Civil War era.

The memorial also displays Stephen Holden Doane's ('66) Medal of Honor, which was given to the school by his family.

The John F. MacMorran Field House, originally built in 1978, provided Tilton with its first indoor hockey arena.