Directed by Phyllida Lloyd with a book by Katori Hall, Frank Ketelaar, and Kees Prins, the musical had its world premiere on 17 April 2018 at the Aldwych Theatre in London.

[1] The musical opens with Tina preparing to go on stage, as she recites a Buddhist chant, nam myoho renge kyo.

Anna Mae's parents have a difficult relationship, and after being physically assaulted, Zelma walks out with her eldest daughter Alline.

Realizing her potential, Ike persuades Zelma to let Anna Mae join his band ("It's Gonna Work Out Fine").

Although Tina enjoys performing with Ike and The Ikettes, she becomes increasingly aware of his vicious temper and possessiveness ("A Fool in Love").

As the band sleeps in the bus, Ike tells Tina about his father who was brutally assaulted for having a relationship with a white woman.

Rhonda Graam is introduced as the band's new manager, and Tina reveals she is pregnant with Raymond's child ("Better Be Good to Me").

As they continue touring, Tina becomes increasingly isolated from Ike as he begins taking drugs and sleeping with other women.

As they drop off a demo tape at Capitol Records, they meet Roger Davies, a young Australian music producer who is a fan of Tina.

Tina feels lonely and isolated, and dreams of Ike watching her ("I Can't Stand the Rain").

[16] The creative team of the musical consists of Katori Hall, with Frank Ketelaar and Kees Prins as writers of the book, Phyllida Lloyd as the director, Mark Thompson as set and costume designer, Anthony van Laast as choreographer and Nicholas Skilbeck as musical supervisor.

Frank Ketelaar and Kees Prins wrote the early draft of the book, with Katori Hall taking over partway through development.

After Warren's departure, the title role has been played by Nkeki Obi-Melekwe,[19] Chanel Haynes,[6][7] Aisha Jawando,[20] Elesha Paul Moses, [21] Kristina Love, Karis Anderson, and Zoe Birkett.

Warren reprised the title role in the Broadway production, with direction by Phyllida Lloyd and choreography by Anthony van Laast.

[37] A non-equity tour kicked off on 24 September 2024, at the E. J. Thomas Hall in Akron, Ohio starring American Idol finalist Jayna Elise.

[38] The musical received generally positive reviews from the critics, with particular praise reserved for Adrienne Warren in the title role as Tina Turner.

"[39] Similarly Dominic Cavendish of The Daily Telegraph described Warren's performance as a "tour de force" and considered the show "slickly choreographed, beautifully designed and roof-raisingly well-sung".

[40] Adam Mattera in Echoes noted "the production plays fast and loose with catalogue chronology... it's a crowd-pleasing decision meaning all the solo mega-hits aren't squeezed into the final act, but simultaneously it derails the dramatic reveal of Tina's 80s rock'n'roll reinvention," while concluding "it's so resounding joyous you don't care.

"[41] Will Gompertz of the BBC criticised the script as "rather disappointingly two-dimensional", but thought the musical "elegantly staged" with Warren a "24-carat, all singing, all dancing, bona fide star".

[42] Stephen Dalton of The Hollywood Reporter noted that while its grand finale contains "stilted, corny elements", "the production becomes a full-blooded rock show that is "roof-raising" and "life-affirming", with a climax that "swept the crowd to its feet.