The document is written in the form of a travelogue and contains descriptions of pilgrim centers throughout India.
The chapter covering North India mentions important places such as Pandarapur, Prayag, Kashi, Gaya, Mathura and Ayodhya.
In addition to holy places, a lot of rivers, including Ganges, Yamuna, Kaveri and Godavari are mentioned.
The Tirtha Prabandha is held in high esteem amongst practising Madhva Hindus and a recitation of all the shlokas is considered equal to an actual pilgrimage covering all the mentioned places.
Some of the holy places mentioned in Tirtha Prabandha are: West: East: South: North : Parishista: