In the 2001 Indian census, the taluk of Tirupathur had a population of 50,455 with 23,656 males and 22,799 females.

It is an important commercial center from time immemorial (whereas Vaniyambadi and Ambur, which were once smaller towns, have recently flourished).

It is well connected by road and rail to other important cities of Tamil Nadu such as Thiruvannamalai, Chennai, Salem, Coimbatore and Vellore and to Bangalore in Karnataka.

This town is also famous in Islamic religious circles as many great saints "Awliyas" had made it their hometown.

There exists a village called Aathiyur (Aathi means Begin) in the southern fringes of the Town and Kodiyur (Kodi means End) in the northern fringes of the town.

Tirupathur's population and land area are good enough to have political representations in the state legislature of Tamil Nadu (Member of the Legislative Assembly), and part of Thiruvannamalai constituency for the central/federal legislature of India (Member of Parliament as of 2009 elections).

The Urban Municipal town spreads over an extent of 9.26 km2; this is a class-I town in Vellore District; is based on population range; floating population is increasing day by day.

There is a century old municipal market having 413 shops which helps in promoting commercial and economic activities of the town.

The town is known for recording coldest temperature in the Tamil Nadu plains during winter.

The town also experiences fairly frequent thunderstorms in late April and May, which gives necessary relief from the heat, along with the dip in night temperatures.

Even a rough estimation cannot easily be established on the origin of Tirupathur town, owing to its antiquity.

During the regimes of various rulers like Cholas, Vijaya Nagara dynasty, Hoysalas the town had been referred to, by the following names: Sri Mathava Chaturvedi Mangalam, Veera Narayana Chaturvedi Mangalam, Tiruperur and Brahmapuram (Brahmeeswaram).

Its entrance might have been near the Kottai Darwaja Sri Veera Anjaneyar Temple, since the word "Kottai" in Tamil means "Fort", and the word "Darwaja" in Hindi/Urdu means "Gate" or "Door".

The town was ruled by Cholas, Pallavas, Hoysalas, Vijaya Nagara rulers, Vallala Maharajan, Sambuvarayars, Tipu, Nawabs of Arcot and undoubtedly by the British.

Due to proximity to the Jolarpet railway junction only few express trains halt here.

The West Coast Express (Mangalore–Chennai Central–Manglore) stops at Tiruppattur railway station every day.