Tiszaeszlár (Old form: Tisza-Eszlár) is a village in Szabolcs-Szatmár-Bereg, Hungary.

In 1882 the village was the centre of blood libel accusations against its Jewish community.

From the 14th to the 18th century, it was partially owned by several families (Biri, Doby, Lónyay, Sztritey, Újfalussy, Tatay, Chernel, Péchy, Ibrányi, Teleky, Zoltán), the longest of whom were the Kállayas.

At the beginning of the 17th century, István Bocskai settled free Hajdús in the village, which was depopulated during the Turkish occupation and had only 49 inhabitants.

Due to the floods on the Tisza, the construction of Újfalu, south of Eszlár, called Ófalu, began to be built in 1858, to which the whole village moved by 1890, and is still located today.