Nikki Calma co-created the persona "Tita Aida" with the Filipino Task Force on AIDS for her role as an auntie, advocate, and HIV/AIDS awareness mentor.

[3] She is currently one of the Managing Directors at the organization in which she also oversees and provides the direction over fifteen HIV services and community programs that is very important for San Francisco.

Among them is TRANS:THRIVE, a drop-in center in San Francisco, California that caters to and serves the transgender community of the Bay Area.

[6] She was also featured in the first PSA developed by and aimed at the wellness of the Asian Pacific Islander transgender community as part of the 20th observance of World AIDS Day.

[10][11] In early 2015, Tita Aida was nominated as a Community Grand Marshal for San Francisco Pride, but was not elected.

[22] She has also MC'd for the Gay Asian Pacific Alliance (GAPA)'s 20th Anniversary Celebration awards banquet in 2008,[23] and its annual fundraiser, RUNWAY, in 2010, 2011,[24] and 2013[25] She hosted the Ms. Tang Tang show,[26] which featured a number of Queer API artists, including D’Lo, Mia Nakano and Kit Yan.