[2] The company holds a United Kingdom Civil Aviation Authority (UK CAA) Type A Operating Licence, permitting it to carry passengers, cargo and mail, on aircraft with 20 or more seats.

[8] In the early 2000s, Titan Airways found an additional niche in the market, pioneering a rapid response Go Now sub-charter service for airlines experiencing operational problems.

[9] Demand by customer airlines for more seats and greater range led to the acquisition of two 757-200s in 2003 and 2005, with one aircraft having a VIP interior for corporate use.

[16] Titan Airways provides short, medium, or long term wet and damp lease operations worldwide to third party carriers.

[19] Aside from these regular seasonal routes, Titan Airways operates long and short haul flights on an ad hoc basis on behalf of individuals, blue chip companies[clarification needed], Premier League football teams, high-profile personalities, and pop/rock groups.

[20] Titan Airways sometimes uses their aircraft in product launches, trade shows, promotional events, and hospitality trips for other companies.

[21] Titan Airways' cooperation with the Royal Mail dates back to the early 1990s, when operations began with the carrier's Short 360 and ATR 42 aircraft.

In 1996, the carrier's BAe 146-200 fleet superseded the smaller aircraft, before being joined, and ultimately replaced, by Titan's Boeing 737-300QCs.

On 30 July 2020, Titan Airways' Boeing 757 became the largest passenger aircraft to land and depart from Saint Helena Airport.

The Air Accidents Investigation Branch (AAIB) determined fuel contamination following defective maintenance undetected for two days had caused the incident.