Titia de Lange (born 11 November 1955, in Rotterdam) is the Director of the Anderson Center for Cancer Research, the Leon Hess professor and the head of Laboratory Cell Biology and Genetics at Rockefeller University.

[4] Titia de Lange attended the University of Amsterdam where she received her bachelor's and master's degree in biochemistry.

[5] She is currently the Leon Hess Professor as well as the Director of the Anderson Center for Cancer Research at Rockefeller University.

In addition to making headway in revealing the structure of DNA, her research has implications for the understanding of aging and cancer.

[5] In her time at the University of Amsterdam she worked for mentor Richard Flavell at the National Institute for Medical Research where she completed her master's thesis.

[8] Her research identified a patient with γβ-thalassemia with a DNA translocation that caused the inactivation of the β-Globin gene.

After receiving her Ph.D. in 1985, de Lange completed a postdoctoral fellowship at the University of California, San Francisco in Harold Varmus's Lab from 1985 to 1990.

Telomeres are repetitive nucleotide sequences at the ends of chromosomes that function as protective elements from improper DNA repair.

[5] In her first several years she dedicated a long amount of time and resources to identifying the major protein components of human telomeres.

[12] With the assistance of Bas van Steensel, de Lange conducted various studies on proteins associated with telomeres.

[14] She and her co-investigators, Bas van Steensel and Agata Smogorzewska, also discovered the protein TRF2 and found that it prevents the end-to-end fusing of telomeres, in addition to other functions.