[2][4] Solis has stayed a babyface character his entire career[5][6] and is best known for his appearances with the World Wrestling Federation between 1979 and 1993 (missing part of 1980 and returning in 1983)[7] where he was a two-time WWF Intercontinental Heavyweight Champion and a two-time WWF Tag Team Championship with Ivan Putski in his first individual reign, and most notably with Rick Martel in his second individual reign.

During his time in the WWF, Solis, despite being born and raised in Mission, Texas, was billed from "Tocula, Mexico", which may be a misspelled reference to the city of Toluca.

Being brought in for TV tapings only, Santana continued to wrestle for GCW until July when he signed for the WWF full time.

Santana finally won the title on February 11, 1984, becoming the first Mexican-American wrestler to win the Intercontinental Heavyweight Championship.

During this time, he started using Valentine's finishing hold, the figure-four leglock and also wrestled in tag-team competition with Blackjack Mulligan.

Santana wrestled at the first WrestleMania, at Madison Square Garden, in March 1985, and in the opening match defeated a masked wrestler known as the Executioner ("Playboy" Buddy Rose), making him submit to the figure four in 4:05.

Wearing street clothes, Santana rushed to the ring to inform referee Dick Kroll that Valentine had used his feet on the ropes to help pin the JYD.

On Right After Wrestling, hosted by Arda Ocal and Jimmy Korderas, Santana stated that he was somewhat disappointed with being in the first match at the original WrestleMania in 1985.

Santana and Valentine went on to wrestle a memorable series of singles and tag team matches with neither gaining the upper hand.

Santana recaptured the Intercontinental Heavyweight Championship from Valentine in a brutal steel cage match in Baltimore on July 6, 1985.

The story for WrestleMania III being that the Bulldogs and Santana wanted revenge on Davis as the one responsible for losing their respective titles.

Santana made a second appearance during Wrestlemania III when he came to the ring and attacked manager Slick after his man "the Natural" Butch Reed had defeated Koko B. Ware.

Martel refused to tag in and walked back to the dressing room leaving Santana to face both opponents alone (the Busters then easily defeated Tito with a Spike piledriver).

In an interview with "Mean" Gene Okerlund immediately following the match, Martel called Santana a loser and said he was sick and tired of carrying him.

Santana even allied with his former archenemies Demolition against Martel, defeating him and The Fabulous Rougeaus in a six-man tag match on June 22, 1989, in Hartford, Connecticut.

As a result, Santana advanced to the final elimination match, teaming with Hulk Hogan and The Ultimate Warrior against Martel, "The Million Dollar Man" Ted DiBiase, The Warlord, and Power and Glory (Hercules and Paul Roma).

This included a dark match loss to Papa Shango at SummerSlam which was held at the Wembley Stadium in London, England.

Santana continued to wrestle through the first half of 1993 following WrestleMania IX, facing Razor Ramon, Adam Bomb, and Papa Shango.

[18] After leaving ECW in 1993, Santana returned to IWCCW in 1994 where he wrestled some of his old WWF rivals such as Hercules Hernandez, Rick Martel, and Greg Valentine.

In IWCCW Santana resumed his feuds from the WWF with Rick Martel and Greg Valentine, and again wrestled Tony Atlas, who defeated him in a match in Yardville, New Jersey.

Santana was slightly considered the top babyface of the company, and its major champion along with Orton (who was the top heel) Santana returned to the WWF as a commentator in the Spanish Broadcast table, He called on Monday Night Raw, as well as PPV events, he was last doing Spanish commentary at WrestleMania XIV.

In November 1997, he made on-air appearances as El Matador in the Karate Fighters Holiday Tournament, facing Carlos Cabrera and Jerry Lawler.

On July 19, 1997, Santana lost by disqualification to "Playboy" Jonathon Luvstruk w/Bodacious Pretty Boy in the finals of the United States title tournament at RCW's Battleground event.

On May 10, 2013, Santana and Tokyo Dragon defeated Mad Russian, Jack Molson and Rich Rogers in a title vs. hair match.

On December 7, 1996, he defeated former WWF rival Bob Orton Jr. to win the USA Pro Heavyweight title.

In July 2012, Santana wrestled in Winnipeg MB for Canadian Westling Elite against Matt Fairlane, but was disqualified due to outside interference.

On September 14, 2012, Santana made an unadvertised appearance for Chikara, when he entered the 2012 King of Trios tournament, teaming with Mihara and The Mysterious and Handsome Stranger, with the three losing to the Spectral Envoy (Frightmare, Hallowicked and UltraMantis Black) in their first round match.

On April 19, 2014, Santana competed in a match with "The German Menace" Kraig Stagg on ECPW's iPPV "Super Showcase Saturday".

On November 25, 2022, Santana competed in his first match in eight years, where he defeated This Guy (Johnny Della Rocka) for BCW 49 in East Burwood, Victoria, Australia.