Užice (Serbian Cyrillic: Ужице, pronounced [ûʒit͡se] ⓘ) is a city and the administrative centre of the Zlatibor District in western Serbia.

[3][2] The region surrounding Užice was settled by Illyrians, specifically the Parthini and the Celtic-influenced Autariatae tribes.

The region (Drina županija) was part of the Vlastimirović dynasty when they established the medieval Principality of Serbia, the first Serb state.

During the reign of the Serbian Emperor Stefan Dušan, Užice is mentioned as a fortress, under the rule of the Vojinović noble family.

Serbian Autokrator Lazar Hrebeljanović and Tvrtko I of Bosnia defeated Nikola Altomanović, and divided his lands between themselves.

By the late 15th century, Ottoman authorities invested in the restoration of the local fortress and encouraged migration into Užice, turning the once village into a town.

Local building's were erected in line with Ottoman architecture and a small Christian population lived in the mahallah of Carina.

[5] In 1690 during the Great Turkish War, Habsburg forces captured Užice and the city fell within the realms of Habsburg-occupied Serbia.

In November 1941, the German army re-occupied this territory, and the majority of Partisan forces escaped to Bosnia, Raška and Montenegro.

In 1974, the Yugoslavian film Ужичка република in Serbian or in English as the Guns of War was released documenting the first offensive in the Great Patriotic War against fascism and follows the Spanish soldier and fervent communist Boro as he organizes a partisan uprising in western Serbia that later establishes itself into the Ужицка Республика / Užička Republika (the Republic of Užice) which lasted 67 days from 24 September to 29 November 1941 (de facto until 1 December 1941) and the defeat of its forces at the battle of Kadinjaca.

From 1992, following the collapse of the pro-communist administration, Titovo (meaning Tito's) was removed, leaving the original city name Užice.

Due to being "Titovo" and central-planning communist system, Užice received significant amounts of investment in infrastructure and local factories, which made the city one of the most highly developed for its size in former Yugoslavia.

The Belgrade-Bar railway passes through Užice and connects it with both the northern parts of Serbia and the Montenegrin coast.

Užice has a fairly developed transportation infrastructure, connected with the surrounding areas by state roads of the first order.

Most companies have factories on the outskirts of the city due to good communication connections, given the close proximity of the main highway, railroad and airport.

The following table gives a preview of total number of registered people employed in legal entities per their core activity (as of 2022):[19] The library and theatre are in the main square in the city centre.

The national museum displays cultural and historical treasures of the city, and with its exhibitions, shows the centuries of rich Užice history.