Tlapallite is a rare and complex tellurate mineral with the chemical formula (Ca,Pb)3CaCu6[Te4+3Te6+O12]2(Te4+O3)2(SO4)2·3H2O.

It was named after the Nahua word "Tlalpalli", which translates to paint, referring to the paint-like habit of the mineral.

It is often found as a thin film on quartz, sericite, calcite or baryte, but it also forms botryoidal aggregates.

[4] It has also been found in the emerald mine in Tombstone District, Cochise County, Arizona in the United States.

It seems to form in the transitory phase when other tellurium minerals, like tlalocite, cesbronite, xocomecatlite, quetzalcoatlite, teineite and carlfriesite, start to break down.