The Tlikakila River (Dena'ina Athabascan Łiq'a Qilanhtnu, literally "salmon-are-there river")[5] is a stream, 51 miles (82 km) long,[3] in the U.S. state of Alaska.

[3] The other two are the Mulchatna and the Chilikadrotna,[3] all added in 1980 to the National Wild and Scenic Rivers System.

The Alaska River Guide describes it as suitable for "intermediate boaters with good wilderness skills".

[4] To reach the floatable parts of the river from Summit Lake, boaters must make a 2-mile (3 km) portage.

[3] Dangers include Class III rapids, which may require a second portage below the confluence with the North Fork Tlikakila River.