The painting depicts the story of Tobit, a righteous Israelite of the tribe of Naphtali, living in Nineveh, who is sent to recover is father's money to Media, escorted by the Archangel Raphael.

The angel instructs the young man to burn the fish's liver and heart to drive away the demon when he attacks on the wedding night.

[5] Tobias and Sarah marry, and the fumes of the burning organs drive the daemon to Upper Egypt, where Raphael follows and binds him.

Surprised to find his son-in-law alive and well, Sarah's father orders a double-length wedding feast and has the grave secretly filled.

[6] De Momper is considered to have made a great contribution to the development of landscape painting in the period between Brueghel and the generation of Rubens.