He played in Major League Baseball (MLB) for the Cincinnati Reds, Milwaukee Brewers, Washington Nationals and Los Angeles Dodgers.

He made his major league debut on April 19, 2005,[1] pitching two innings and giving up two runs against the Chicago Cubs.

[3] He picked up his first win in a two inning relief appearance against the San Diego Padres on May 10, 2005, and his first save against the Pittsburgh Pirates on August 28, 2005.

[5] On April 22, 2009, Coffey made an appearance as the closer for the Brewers; he held the role until Trevor Hoffman returned from an injury.

On July 3, it was announced that Coffey would undergo Tommy John surgery for the second time of his career and miss the rest of the 2012 season.

[9] He served as the closer for the Mariners' Triple-A team the Tacoma Rainiers for the remainder of the season, and was released on September 4.

graphic on the scoreboard that kept track of Coffey's time to sprint from the bullpen to the pitcher's mound after getting called out to pitch.