Todd Mission is a city in Grimes County, Texas, United States.

It lies on Farm to Market Road 1774, fifty miles (80 km) northwest of Houston.

The racial makeup of the city was 80.82% White, 3.42% African American, 15.75% from other races.

There were 6.5% of families and 10.4% of the population living below the poverty line, including 18.2% under eighteen years and 33.3% over 64.

Todd Mission is served by the Navasota Independent School District.