[10] Its dome-shaped roof is an air-supported structure, a cable-reinforced 0.8 mm flexible fiberglass membrane supported by slightly pressurizing the inside of the stadium[11] with 150,000 m3/hour[12] using independent blowers.

This was because the Japan Series had to be rescheduled due to the spread of COVID-19 infectious disease, and the dates overlapped with the game days of amateur baseball tournaments at Meiji Jingu Stadium.

This amusement park occupies the former Korakuen Stadium site and includes a roller coaster named Thunder Dolphin and a hubless Ferris wheel.

Four years later, the New York Yankees, featuring former Yomiuri Giants slugger/outfielder Hideki Matsui in their lineup, and the Tampa Bay Devil Rays played two games in the stadium to start the 2004 season.

The Boston Red Sox and the Oakland Athletics opened the 2008 MLB season in Japan, and also competed against Japanese teams.

[20][21] To open the 2012 season the Seattle Mariners and the Athletics, the former of which had Ichiro Suzuki, played a two-game series on March 28–29.

[23][24] On July 18, 2024, Major League Baseball announced that the 2025 MLB season will open with a two game series March 18-19 at Tokyo Dome between the Los Angeles Dodgers and the Chicago Cubs.

[26] Concerts have been held at Tokyo Dome for several dozen days each year since its opening, mainly by Japanese singers and music groups.

As part of the second leg of his Bad World Tour, he performed at the Tokyo Big Egg on December 9-11, 17-19, and 24-26, 1988.

Mariah Carey performed there for the first time on her Daydream World Tour, on the 7, 10 and 14 of March in 1996, bringing in a total of 150,000 people with the 3 dates, she obtained the record for best-selling tickets in less than 1 hour.

In 1998, the singer returned to Japan on her Butterfly World Tour, where she broke her old record, this time selling out 200,000 tickets in less than 1 hour, there were 4 shows, on January 11, 14, 17 and 20.

[30] The final round of the K-1 World Grand Prix kickboxing tournament was held at Tokyo Dome from 1997 to 2006.

As part of the American Bowl, Tokyo Dome held 13 National Football League preseason games between 1989 and 2005.

[31] In the 1996 game between the San Diego Chargers and Pittsburgh Steelers, three Japanese linebackers – Takuro Abe, Shigemasa Ito, and Takahiro Ikenoue of the World League of American Football – became the first Japanese players to participate in an NFL game; Abe and Ito sporadically appeared on special teams for the Chargers, while Ikenoue was part of the Steelers' defense.

In December 1993, the Wisconsin Badgers clinched the Big Ten college football championship and a berth to their first Rose Bowl in 31 years by defeating the Michigan State Spartans 41-20 in the last Coca-Cola Classic, before nearly 52,000 at Tokyo Dome.

In 1989, the United States Hot Rod Association hosted one of the first monster truck rallies outside North America at Tokyo Dome.

On February 26, 2023, Japanese figure skater and two-time Olympic champion, Yuzuru Hanyu, held a solo ice show titled Gift at Tokyo Dome.