He attended Benedictine High School in Cleveland and Ohio State University, where he played on the golf team.

Weiskopf's first win on the PGA Tour came at the 1968 Andy Williams-San Diego Open Invitational and fifteen more followed by 1982.

[3] Weiskopf won the Canadian Open in 1973 and 1975, the latter win was achieved in dramatic fashion with a one-hole playoff win over archrival and fellow Ohio State University alum Jack Nicklaus when Weiskopf nearly holed his approach on the 15th hole at the Royal Montreal Golf Club's Blue Course.

He hit the ball high, generated enormous power and had very good control as well which is a rare combination.

[5] In January 2016, it was announced that Weiskopf would lead a renovation of the Torrey Pines North Course in San Diego, California.

[8] His death was first announced by fellow golfer Tom Watson, who extended his condolences to the Weiskopf family in a tweet.