Especially in Dello occhiale (Venice: Carempello, Sandro Bazacchi, 1627), Stigliani laments Marino's many “failures” in the poem Adone.

Marino refused, Stigliani indignantly points out, to follow Aristotle's unities, ignoring the need for a proper beginning, middle, and an end.

In 1617 Stigliani published in Piacenza Il Mondo Nuovo, an epic poem about the discovery of America owing a good deal to the Italian Romance tradition.

In his depiction, Stigliani merges a detailed description of America with characters and situations that are closer to the realities of life in seventeenth-century Europe, creating a bridge between the two continents.

The description of the newt that lives in the Rio de la Plata is a way to make fun of his archenemy Giambattista Marino; the execution of the amazons in the poem is a criticism of the behavior of his patron Ranuccio Farnese; the mad people of the island of Brandana mirror the behavior of all the princes and courtiers who occupy every European Renaissance court.