[5][6] St Helens reached the 2014 Super League Grand Final, and Makinson was selected to play on the wing, scoring a try in their 14–6 victory over the Wigan Warriors at Old Trafford.

[11] He played in the 2019 Super League Grand Final victory over the Salford Red Devils at Old Trafford, slotting a stunning drop goal in the process.

[15] Makinson played in the club's 8-4 2020 Super League Grand Final victory over Wigan at the Kingston Communications Stadium in Hull; his 80th minute drop-goal attempt rebounded off the goal sticks and led to the winning try.

[21] In the 2022 semi-final, Makinson was sent to the sin bin for a professional foul during St Helens' 19-12 victory over Salford which sent the club into their fourth consecutive grand final.

[34] Makinson enjoyed a stellar 2018 season, being included in the Super League Dream Team and playing a starring role in England's 2–1 series victory over New Zealand.

[35] In November 2018 he won the Rugby League World Golden Boot Award over James Tedesco, Dallin Watene-Zelezniak and Elliot Whitehead.

[36] On 15 October 2022, Makinson scored one try and kicked ten goals in England's opening game of the 2021 Rugby League World Cup against Samoa.

[37] In the quarter-final of the 2021 Rugby League World Cup, Makinson became the first player to score five tries for England in a game as they won 46-6 against Papua New Guinea.