TPU was a member of 12 international associations, including the Conference of European Schools for Advanced Engineering Education and Research (CESAER) until it was suspended in March 2022, and the European University Association (EUA) until it was suspended in March 2022.

The University main building was constructed in 1897-1907 based on a project by Robert Marfeld, an academician of architecture.

In January 1899, in accordance with the Supreme Decree of the Department of Civil and Ecclesiastical Administration, a student of Mendeleev, Professor Efim Zubashev was appointed the first Rector and Chairman of the Construction Committee to erect premises of Tomsk Technological Institute.

On March 5, 1935, in accordance with the All-Union Central Executive Committee of the USSR, the Institute was named after Sergey Kirov.

[citation needed] In 1941-45 during the battles at the Eastern Front of World War II, all research work of the Institute was focused on the development of the arms industry, the assistance to arms production, including to evacuated industrial enterprises in Tomsk.

Timofey Gorbachev, a 1928 alumnus of Dzerzhinsky Siberian Technological Institute, headed the department of the Kuzbassugol Building Complex.

Nikolay Kamov, a 1923 alumnus of the Mechanical Faculty of Tomsk Technological Institute, became chief engineer at the Design Bureau producing helicopters.

From 1943 till the end of the battles at the Eastern Front, the mine maintained the ideals of the USSR State Defense Committee.

[citation needed] In 1962, Tomsk Institute of Radioelectronics and Electronic Technology was set up based on the TPU Radio Engineering Faculty.

On October 18, 1991, the Council of Ministers of the Russian Soviet Federative Socialist Republic adopted resolution No.

On the basis of various TPU faculties, departments and majors, over 20 free-standing universities in Moscow, Novosibirsk, Omsk, Tomsk, Seversk, Krasnoyarsk, Kemerovo, Barnaul, Chita, Khabarovsk and other Russian cities were opened at different time.

[citation needed] Dmitry Andreevich Sednev, Rector of the university, was suspended by the European University Association (EUA) following support for the 2022 Russian invasion of Ukraine by the Russian Union of Rectors (RUR) in March 2022, for being "diametrically opposed to the European values that they committed to when joining EUA”.

A key point of the program of TPU was announced the formation of high school as a world-class university-based staffing and development of technologies for resource-efficient economy.

TPU envisages university development in the field of resource-efficient technologies that unites six research and educational clusters: TPU was a member of 12 international associations, including the Conference of European Schools for Advanced Engineering Education and Research (CESAER) until it was suspended in March 2022, and the European University Association (EUA) until it was suspended in March 2022.