Written and directed by series co-creator Trey Parker, it first aired on Comedy Central in the United States on March 12, 2008.
The episode is a satire on the new and effective AIDS treatments that are inaccessible to the majority of the population suffering from or carrying the disease.
A benefit is held for Cartman, but is sparsely attended as most people are apathetic to AIDS and cancer has become more focused on.
Johnson allows some of his money to be used in research for a cure, and scientists experiment with a concentrated dose of $180,000, which successfully neutralizes HIV particles.
During most of the episode, Cartman wears an outfit similar to one worn by Andrew Beckett, a fictional character portrayed by Tom Hanks in Philadelphia (1993).
"[4] Brad Trechak of TV Squad also gave a mixed review, saying that "Overall, a good show with some great one-liners.
The sets included brief audio commentaries by Parker and Stone for each episode, a collection of deleted scenes, and two special mini-features, The Making of 'Major Boobage and Six Days to South Park.