[4][5] He worked for several years as a scientist at various jobs, including studying cranio-facial defects in developing zebrafish embryos at Chicago's Children's Memorial Hospital.

[15] Several critics have praised the comic range of Sam's voice; Jake Kroeger of website The Comedy Bureau wrote that it "is so unique, drastically wandering up and down in frequency, that he makes [his] characters exceptionally hilarious and absolutely unforgettable".

with Michael McKean and a producer for Josh Gates Tonight, Expedition Unknown, Jay Leno's Garage, Girl Meets Farm, Storage Wars: Barry Strikes Back, Brandi & Jarrod: Married to the Job, MTV's Ridiculousness[17] and the Netflix hit home-renovation show, Instant Dream Home,[17] which in 2023 was nominated and won the Daytime Emmy Award for "Outstanding Instructional and How-To Program".

[29][30] He has also guested on many other podcasts, including Jackie Kashian's The Dork Forest,[3] Josh Adam Meyers' The 500,[31] Probably Science,[32] Dumb People Town and Sklarboro County with the Sklar Brothers,[33] and The Space Cave with David Huntsberger.

[34] It received generally positive reviews and praise from several high-profile comics including Kyle Kinane, Michelle Buteau, The Sklar Brothers, Beth Stelling, Jason Nash, former SNL cast member, Brooks Wheelan, Brody Stevens and Eddie Pepitone.

[35] Jake Krueger of the Los Angeles based review site, The Comedy Bureau, called the album one of the best of 2014,[36] saying it "strikes a great balance between a genuine silliness and unfiltered candor".

[40] Chris Spector of Midwest Record wrote that "Sam does a fine job of being that normal guy that lives next door that suddenly, unexpectedly goes nuts.