Tooth and Nail is a 1992 crime novel by Ian Rankin, originally entitled Wolfman.

Rebus is drafted in by the Metropolitan Police to help track down a cannibalistic serial killer called the Wolfman, whose first victim was found in the East End of London's lonely Wolf Street.

His London colleague, George Flight, is not happy at what he sees as interference, and Rebus encounters racial prejudice as well as the usual dangers of trying to catch a vicious killer.

When Rebus is offered a psychological profile of the Wolfman by an attractive woman, it seems too good an opportunity to miss.

In the Exile on Princes Street foreword to Rebus: The Early Years, Rankin says he was living in London at the time of writing and didn't enjoy it, so "I brought Rebus to London so he could suffer, too".