Topoľovka is a village and municipality in Humenné District in the Prešov Region of north-east Slovakia.

In historical records the village was first mentioned in 1479.

The municipality lies at an altitude of 157 metres (515 feet) and covers an area of 7.777 square kilometres (3.003 square miles).

Topoľovka is twinned with:

This Prešov Region geography article is a stub.