[5] Located in the southeastern suburb of Rome, the university combines a liberal arts tradition with emphasis on career orientation in the field of Economics, Engineering, Mathematics and Physics, Natural Sciences, and Medicine.

[6] It was established in 1982 with the goal of providing high-quality education for students preparing to meet the changing needs and opportunities of the workforce.

[9][10] The university takes its name from the 14th-century farmhouse "Turris Virgata" that was owned by the Roman noble Annibaldi family, whose remains lie beneath Villa Gentile on campus.

The university occupies a 6-square-kilometre (1,483-acre) area outside the Grande Raccordo Anulare highway connection, in the eastern sector of the city.

Near the university, there are accommodation facilities owned by the regional organization Lazio DiSCo[11] as well as Campus X, a private company.

Campus X accommodations, rolled out in October 2010,[12] now consist of over 1300 bed spaces[13] for students and researchers, as well as study rooms, a market, a restaurant, a gym, a music recording studio and many other facilities.

On February 14, 2012, the Italian Prime Minister Mario Monti called an end to the bid, citing uncertain costs and unknown financial benefit.

The new university tower, located on the opposite side of the road with respect to the City of Sport project, will rise to about 90 meters, whose penultimate floor would host the new administrative office of Tor Vergata, while the top floor would host a wide lobby that would offer panoramic views.

The university is divided into six schools: Economics, Engineering, Humanities, Law, Mathematics, Physics and Natural Sciences, and Medicine and Surgery.

[2] The university has taken significant steps in the past years to participate in international projects and to link industries to its research.

CEIS is engaged in creating and supporting international research and higher-learning networking in the major fields of economics.

[22] CEIS hosts numerous seminars and conferences bringing together leading economists and experts in academia and government.

The main aim of this programme is to create 'European Universities' based on cross-border alliances of higher education institutions in order to share a long-term strategy and promote European values and identity, by creating a European university campus for the purpose of promoting students' physical and virtual mobility.

[56][57] Hand in hand with this aim goes the YUFE Diploma Supplement Track, rolled out in November 2020, a diploma supplement that acknowledges all the activities, projects and accomplishments, such as academic courses, professional training, etc, that students are given the chance to take part in across the various YUFE universities.