It stars Kiyoshi Atsumi as Torajirō Kuruma (Tora-san), and Keiko Matsuzaka as his love interest or "Madonna".

[2] Tora-san's Love in Osaka is the twenty-seventh entry in the popular, long-running Otoko wa Tsurai yo series.

[5] For her role in the film Keiko Matsuzaka was named Best Actress at the Japan Academy Prize and Blue Ribbon Awards.

[8] Stuart Galbraith IV writes that Tora-san's Love in Osaka is an "above-average entry in this consistently excellent series".

Director Yamada, according to Galbraith, "obviously favors rural, remote Japan to sprawling urban landscapes like Osaka," but nevertheless, "the film plays as a heartfelt valentine to the city and its people.