[10] The following day, the SPC noted the increased potential for organized severe thunderstorms in the region extending from southeastern Arkansas northeast into southern Indiana, upgrading that area to an enhanced risk.

At 5:51 p.m. CST, the National Weather Service office in North Little Rock issued the first tornado warning associated with the storm for portions of Jackson, Lawrence, White, and Woodruff counties.

[22][23] By the pre-dawn hours of December 11, a decrease in instability led to a gradual weakening of a line of thunderstorms stretching along the associated cold front from eastern Kentucky southward into central Alabama.

[26] The National Weather Service (NWS) issued a total of 149 tornado warnings throughout the night across nine states: Arkansas, Tennessee, Missouri, Mississippi, Kentucky, Illinois, and Indiana.

The Monette Manor nursing home lost most of its roof and had masonry exterior walls knocked down, killing one person and trapping 20 other residents and employees, including five people who were injured.

The tornado then crossed into Pemiscot County west of Steele at high-end EF2 intensity, snapping and denuding trees, downing power poles, heavily damaging a couple of homes, and tossing a pickup truck.

The large wedge tornado then weakened but remained strong as it crossed I-55 just south of Hayti at EF2 intensity, blowing multiple semi-trailer trucks off the highway into a field, injuring the drivers.

Outbuildings and barns at that location and neighboring properties were completely destroyed, large trees were snapped, livestock was killed, and another house sustained destruction of its attached garage.

More trees were downed at EF1 intensity as the tornado moved east, before it crossed the Missouri River for the last time into areas north of the Creve Coeur Airport and an adjacent sports complex.

The tornado was initially weak, with damage at the beginning of the path being limited to downed highway signs, a bent light pole, and some orange construction barrels that were tossed around.

It struck an Amazon warehouse along Chain Of Rocks Road, where night workers were beginning their shifts and several employees were attending a Christmas party being held as the tornado approached the facility.

The tornado crossed into Kentucky near the community of State Line and rapidly intensified to EF4 strength as it struck Cayce at about 9:00 p.m. CST (03:00 UTC), where major damage occurred to homes, businesses, a school building, and the town's fire station.

[65][66][67][68][69] Closely paralleling Purchase Parkway and US 45 into Graves County, the tornado moved directly toward Mayfield, entering the southwestern portion of the city at 9:25 p.m. CST as it reached EF4 intensity.

[70][20][71] Catastrophic damage occurred as the violent tornado tore directly through the Mayfield Downtown Commercial District at near high-end EF4 intensity, where numerous large, well-built brick buildings were destroyed, many of which completely collapsed and were left as piles of rubble.

Hundreds of large trees were snapped, denuded, and debarked throughout Mayfield, numerous power lines were downed, and the town's emergency operations center lost the ability to transmit radio communications.

About 110 people were left trapped at the Mayfield Consumer Products candle factory when the tornado hit the facility, completely flattening the building to the ground and tossing industrial vehicles.

The tornado crossed the Rough River a total of eleven times in Ohio, Grayson and Breckinridge counties, producing EF1 to EF2 damage to many structures, and downing countless trees along its northeastward track.

[89] Exiting Newbern and moving to the northeast, the tornado weakened to EF1 intensity and crossed into Gibson County, where tree damage occurred and a house along Cool Springs Road had part of its roof blown off.

Farther northeast, EF3 damage continued as a well-built brick home along Blake School Road was completely shifted off of its foundation, with its deck destroyed and several walls knocked down.

Damage surveyors determined that the extent of the destruction noted at the homes and duplexes was more due to heavy debris impacts, rather than extreme winds, and a rating of high-end EF2 was applied in this area as a result.

It then clipped the south edge of the Western Kentucky University campus, where the buildings were not directly hit by tornadic winds, but debris was found speared into the exterior walls of a few structures.

It then crossed the Barren River and regained low-end EF2 strength as it destroyed a brick silo and inflicted considerable roof damage to some houses and apartment buildings to the south of Old Porter Pike.

A gas station canopy, a Wendy's sign, and some storage garages were also damaged near the plant, and a fully loaded tractor-trailer was flipped onto its side and pushed about 15 yards (14 m) from where it originated into the front of a restaurant.

The tornado then crossed KY 289 at mid-range EF2 strength and moved through a series of fields and wooded areas, snapping or uprooting numerous trees, damaging the roof of a house, and destroying an outbuilding.

A double-wide mobile home was destroyed, a two-story house suffered major damage to its roof and attached garage, and many trees and several power poles were snapped along this segment of the path.

The Twin Cities received a maximum total of 21 inches (53 cm) of snow, making the winter storm the heaviest snowstorm recorded in the area since another blizzard in April 2018.

[128] Western Kentucky University canceled commencement ceremonies scheduled for December 11, due to the EF3 tornado that hit Bowling Green the previous night and caused citywide power outages affecting the campus.

[79][134] Employees at the National Weather Service's St. Louis office, located in Weldon Spring, were forced to take shelter and temporarily suspend operations as an EF3 tornado passed just south of the facility around 7:45 p.m. CST on December 10.

[142] Recovery efforts are currently underway, as disaster-aid and humanitarian groups, such as the American Red Cross, The Salvation Army, Adventist Community Services, and World Vision are collecting donations and traveling to or shipping relief items to affected areas to provide aid.

[153][154] An Amazon employee from near Campbellsville, Kentucky, went viral on Twitter after being turned around by police and being unable to reach the warehouse for her shift due to search and rescue efforts and damage from an EF3 tornado in Taylor County.