[1] The series follows the 2005 30-day 20-show stand-up comedy tour featuring Dane Cook and three of his best friends in the industry: Robert Kelly, Gary Gulman, and Jay Davis.

Gary Gulman left the tour because of unknown reasons, but returned after a few dates.

At each destination Dane Cook and fellow comedians play a game or do an activity before performing.

Tourgasm is very similar in format to the Showtime/Comedy Central film and short series The Comedians of Comedy.

The song heard in the beginning and end credits is "Dimension" by Australian rock-band Wolfmother.