The airport dates back to World War I, being established as a French Air Force (Armee de l'Air) training center.

Later it developed into a center of training for all aerial observers of the Air Service, United States Army assigned to the AEF.

[4] After World War II the airport was used by NATO and the US Air Force before becoming a flying school in the 1950s.

During the end of the 1970s the airport enjoyed a golden period due to the local airline Touraine Air Transport (TAT), but that airline suffered a slow slump, from which the airport never really recovered until the late 1990s, when it received subventions by the Conseil Général.

The following airlines operate regular scheduled and charter flights at Tours Val de Loire Airport: