The film's ensemble voice cast includes Tom Hanks, Tim Allen, Joan Cusack, Don Rickles, Wallace Shawn, John Ratzenberger, Estelle Harris, Jeff Pidgeon, Jodi Benson, John Morris, Laurie Metcalf, and R. Lee Ermey.

The toys escape and, believing Andy intended to throw them away, join Barbie in a donation box bound for Sunnyside Daycare.

After Andy's toys endure a rough playtime with the toddlers, Buzz asks Lotso to have himself and his friends moved to the older children's room, but is instead captured.

That night, Andy's toys initiate an escape plan, inadvertently accidentally resetting Buzz to Spanish mode in the process.

Andy's other toys jump in to help, and fall into the truck, where a junked television hits Buzz and restores him to his normal persona.

Woody and his friends ride another garbage truck, driven by an adult Sid Phillips, back to Andy's house.

In addition to the main cast, Toy Story 3 features Jeff Pidgeon as the Aliens, R. Lee Ermey as Sarge and Blake Clark as Slinky, Andy's other toys; Laurie Metcalf and Bea Miller as Andy's mother Mrs. Davis and sister Molly; Emily Hahn and Lori Alan as Bonnie and her mother; Erik von Detten as Sid, a garbage truck driver; and Javier Fernández Peña as Spanish Buzz.

[7] Bonnie's toys are voiced by Timothy Dalton as Mr. Pricklepants; Kristen Schaal as Trixie; Jeff Garlin as Buttercup; Charlie Bright, Amber Krone and Brianna Maiwand as the Peas-in-a-Pod; and Bud Luckey as Chuckles.

[8] The Sunnyside Daycare toys are voiced by Lee Unkrich as the jack-in-the-box, Teddy Newton as Chatter Telephone, Woody Smith as Big Baby,[9][10] Whoopi Goldberg as Stretch, Jack Angel as Chunk, Jan Rabson as Spark and Richard Kind as the Bookworm.

While searching on the Internet, they then discovered that many more Buzz Lightyear toys are malfunctioning around the world and the company had issued a massive recall.

[19] The studio's brain trust, which included John Lasseter, Andrew Stanton, Pete Docter, and Lee Unkrich, had their own idea for a sequel that they had carried around for years.

[20][21][22] This story had no traces of the Circle Seven version of the film since the filmmakers did not read its script: "Not out of spite, but we wanted to start fresh, and not be influenced by what they'd done," said Unkrich.

[25] In February 2008, the film's plotline was reported: "Woody the cowboy and his toy-box friends are dumped in a daycare center after their owner, Andy, leaves for college.

[28] Instead of sending Tom Hanks, Tim Allen, and John Ratzenberger scripts for their consideration in reprising their roles, a complete story reel of the film was shown to the actors in a theater.

[58][59] Toy Story 3's "Not since..." Oscar campaign drew a lot of attention, emphasizing the film's uniqueness and critical acclaim.

The campaign consisted of posters featuring characters from the film, comparing Toy Story 3 to previous winners such as The Lord of the Rings: The Return of the King, Shakespeare in Love, Titanic, and more.

[60] Walt Disney Studios Chairman Rich Ross explained they were going for the Best Picture win, not just Best Animated film.

[62] Toy Story 3 was released by Walt Disney Studios Home Entertainment in North America on November 2, 2010, in a standard DVD edition, a two-disc Blu-ray Disc, and in a four-disc Blu-ray/DVD/Digital Copy combo pack.

[68] In the United Kingdom, it broke the record for the largest first day ever for an animated feature in sales revenue, on both DVD and Blu-ray.

[96] It set opening-weekend records for animated films in Ecuador, Colombia, Mexico, China, Argentina,[97] Hong Kong,[98] Spain, and the UK.

The site's critical consensus reads, "Deftly blending comedy, adventure, and honest emotion, Toy Story 3 is a rare second sequel that really works.

[106] A. O. Scott of The New York Times stated "This film—this whole three-part, 15-year epic—about the adventures of a bunch of silly plastic junk turns out also to be a long, melancholy meditation on loss, impermanence and that noble, stubborn, foolish thing called love.

"[107] Owen Gleiberman from Entertainment Weekly gave the film an "A" saying "Even with the bar raised high, Toy Story 3 enchanted and moved me so deeply I was flabbergasted that a digitally animated comedy about plastic playthings could have this effect.

[109] Michael Rechtshaffen of The Hollywood Reporter also gave the film a positive review, saying "Woody, Buzz and playmates make a thoroughly engaging, emotionally satisfying return.

"[110] Mark Kermode of the BBC gave the film, and the series, a glowing review, calling it "the best movie trilogy of all time.

"[111] In USA Today, Claudia Puig gave the film a complete 4-star rating, writing "This installment, the best of the three, is everything a movie should be: hilarious, touching, exciting, and clever.

"[112] Michael Phillips of the Chicago Tribune gave the film 3 out of 4 stars, writing that "Compared with the riches of all kinds in recent Pixar masterworks such as Ratatouille, WALL-E, and Up, Toy Story 3 looks and plays like an exceptionally slick and confident product, as opposed to a magical blend of commerce and popular art.

[115] At the 83rd Academy Awards, Toy Story 3 received nominations for Best Picture, Best Adapted Screenplay, and Best Sound Editing; and won Best Animated Feature and Best Original Song.

According to Screen Crush, Pixar's parent company Walt Disney Studios gave the McGrews permission to release the film online.

[135] It marginally surpassed the box-office take of Toy Story 3,[136] and received a similarly positive critical and audience response.