The 4.0 L (3,969 cc; 242.2 cu in) all-alloy 1UZ-FE debuted in 1989 in the first generation Lexus LS 400/Toyota Celsior and the engine was progressively released across a number of other models in the Toyota/Lexus range.

[2] It has proven to be a strong, reliable and smooth powerplant with features such as 6-bolt main bearings and belt-driven quad-camshafts.

[citation needed] In its original, Japanese domestic market trim with 10.0:1 compression, power output is 191 kW JIS (256 hp; 260 PS), torque of 353 N⋅m (260 lb⋅ft).

[4][5] Applications (calendar years): The 2UZ-FE was a 4.7 L; 284.6 cu in (4,663 cc) version built in Tahara, Aichi, Japan and at Toyota Motor Manufacturing Alabama.

Unlike its other UZ counterparts, this version uses a cast iron block to increase durability, as it was designed for low-revving, high-torque pickup and SUV applications.

Applications (calendar years):[7] Toyota Racing Development offered a bolt-on supercharger kit for the 2000–2003 Tundra/Sequoia and the 1998–2003 LX 470.

[8] Applications (calendar years):[2] In 1997, the US Federal Aviation Administration granted production certification for the FV2400-2TC, a twin-turbocharged airplane powerplant based on the 1UZ-FE.

[9] The 360 hp (268 kW; 365 PS) FV2400 was developed in partnership with Hamilton Standard, which provided the digital engine-control system.