Trần Quang Khôi (24 January 1930 – 1 April 2023) was a Brigadier general in the South Vietnamese Army of the Republic of Vietnam (ARVN).

He obtained a Master of Military Arts and Sciences (MMAS) degree from US Army, Command and General Staff College in Fort Leavenworth, Kansas, class of 1972–1973.

His Military education included: the French Cavalry School at Saumur in 1955 (Advanced Course), the US Army Armor School at Fort Knox in 1959 (Advanced Course), and the US Army Command and General Staff College at Fort Leavenworth in 1972–1973 In early 1970, his combined-arms Task Force 318 spearheaded the US/VN incursion into Cambodia destroying large NVA logistical installations and damaging heavily NVA main forces.

In November 1970, he organized, trained 3rd Armored Cavalry Brigade and commanded it in Cambodia to secure the border against NVA infiltrations into III Corps area.

In the morning of 30 April 1975, the IIICAF left Bien Hoa rushed to rescue Saigon but had to stop the fighting when BG Khoi heard the President’s voice on the radio ordering all ARVN to cease fire and surrender.